Luukkainen R, Hakala M, Sajanti E, Huhtala H
Department of Rheumatology, Satalinna Hospital, Harjavalta, Finland.
Eur J Rheumatol Inflamm. 1994;14(2):1-4.
The predictive value of synovial fluid (SF) analysis and some other variables for the efficacy of intra-articular corticosteroid therapy of knee joints in 20 patients with spondylarthropathy and hydropsy in a knee joint was estimated in a prospective study. The knee joints were initially aspirated and 30 mg triamcinolone hexacetonide injected intra-articularly. The tenderness scores and the circumferences of the knee joints were measured at the start and after the two months follow up period. Between the patients with and without improvement in tenderness scores of the knee joints SF protein (p = 0.021), SF lactate (p = 0.033), SF IgG (p = 0.018) and SF IgM (p = 0.047) differed significantly, all being lower in patients with improved tenderness scores. There were no significant differences in the variables between patients with at least 2 centimetres decrease of knee joint difference and those with less during follow up.
在一项前瞻性研究中，评估了20例脊柱关节病合并膝关节水肿患者的滑液（SF）分析及其他一些变量对膝关节腔内注射皮质类固醇治疗效果的预测价值。首先对膝关节进行穿刺抽吸，然后关节腔内注射30mg曲安奈德己酸酯。在开始时和两个月的随访期后测量膝关节的压痛评分和周长。膝关节压痛评分有改善和无改善的患者之间，滑液蛋白（p = 0.021）、滑液乳酸（p = 0.033）、滑液IgG（p = 0.018）和滑液IgM（p = 0.047）存在显著差异，压痛评分改善的患者这些指标均较低。随访期间膝关节周长至少减少2厘米的患者与减少较少的患者之间，这些变量无显著差异。
