Kremser B G, Falk M, Kieselbach G F
Universitätsklinik für Augenheilkunde, Universität Innsbruck, Osterreich.
Ophthalmologica. 1995;209(2):60-3. doi: 10.1159/000310581.
The influence of serum lipid fractions [triglyceride, cholesterol, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol] on the visual outcome after central laser photocoagulation of 39 patients (65 eyes) with clinically significant macular edema was investigated in a prospective study. Referring to normal Austrian serum lipid levels, the patients were classified into a normal and a pathological group for each of the 4 lipids. Concerning triglycerides and HDL cholesterol, the normal group (triglyceride < 2.29 mmol/l, HDL cholesterol > 1.3 mmol/l) showed a statistically significantly better visual outcome than the pathological group. Also, patients with normal total cholesterol and LDL cholesterol values tended to achieve better results after treatment. We therefore conclude that serum lipid fractions may influence not only the success of laser treatment but also the course of diabetic macular edema.
在一项前瞻性研究中，对39例（65只眼）患有临床显著性黄斑水肿的患者进行了中心激光光凝治疗，研究了血清脂质成分[甘油三酯、胆固醇、高密度脂蛋白（HDL）胆固醇、低密度脂蛋白（LDL）胆固醇]对视觉预后的影响。参照奥地利正常血清脂质水平，将患者按4种脂质中的每一种分为正常组和病理组。对于甘油三酯和HDL胆固醇，正常组（甘油三酯<2.29 mmol/l，HDL胆固醇>1.3 mmol/l）的视觉预后在统计学上显著优于病理组。此外，总胆固醇和LDL胆固醇值正常的患者在治疗后往往取得更好的结果。因此，我们得出结论，血清脂质成分不仅可能影响激光治疗的成功率，还可能影响糖尿病性黄斑水肿的病程。
