Lisker Melman M, Coté C
Departamento de Gastroenterología y Clínica de Hígado, Instituto Nacional de la Nutrición Salvador Zubirán, México, DF.
Rev Gastroenterol Mex. 1993 Apr-Jun;58(2):154-63.
In the last three decades we have reinforced our knowledge of the biology, natural history and serology of viral hepatitis. The available serologic tests allow us to determine the state of the disease (acute or chronic), the replicative state of the virus and in some cases to predict prognosis. Serologic assays are technically easy and fast, and generally do not represent any interpretation problem. Advances in molecular biology has permitted the discovery of mutants and new serotypes, as well as the elaboration of assays capable of detecting genomic amounts of specific nucleic acids for further characterization of the hepatitis viruses. This means we are, again, at the beginning of a new area.
在过去三十年里，我们加强了对病毒性肝炎生物学、自然史和血清学的认识。现有的血清学检测使我们能够确定疾病状态（急性或慢性）、病毒复制状态，在某些情况下还能预测预后。血清学检测在技术上简便快捷，通常不存在任何解读问题。分子生物学的进展使人们发现了突变体和新血清型，还研发出了能够检测特定核酸基因组数量的检测方法，以便对肝炎病毒进行进一步特征分析。这意味着我们又处于一个新领域的开端。
