Kodentsova V M, Vrzesinskaya O A, Spirichev V B
Institute of Nutrition, Russian Academy of Medical Sciences, Moskow.
Ukr Biokhim Zh (1978). 1994 Sep-Oct;66(5):17-22.
This review concerns recent experimental information on some aspects revealing biochemical nature of the origin of defects responsible for the spermatozoa's loss of fertilizing potential. Possible protective effect of vitamins-antioxidants against peroxidative damage of spermatozoa playing a key role in the etiology of defective sperm function, regulating role of vitamins K and D in MM-isozyme creatine kinase activity serving as a measure of sperm biochemical maturity and normal sperm development and influence of body insufficiency of B group vitamins on energy metabolism disturbances in motile, actively metabolizing spermatozoa have been discussed.
本综述涉及近期一些实验信息，这些信息揭示了导致精子受精潜力丧失的缺陷起源的生化本质。讨论了维生素抗氧化剂对精子过氧化损伤的可能保护作用，这种损伤在精子功能缺陷的病因中起关键作用；维生素K和D对MM同工酶肌酸激酶活性的调节作用，该酶活性可作为精子生化成熟和正常精子发育的指标；以及B族维生素身体不足对活动的、积极代谢的精子能量代谢紊乱的影响。
