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西米德兰兹郡亚洲传统疗法导致的铅中毒——5例系列病例报告

Lead poisoning from Asian traditional remedies in the West Midlands--report of a series of five cases.

作者信息

Bayly G R, Braithwaite R A, Sheehan T M, Dyer N H, Grimley C, Ferner R E

机构信息

National Poisons Information Service (Birmingham Centre), Dudley Road Hospital, Birmingham, UK.

出版信息

Hum Exp Toxicol. 1995 Jan;14(1):24-8. doi: 10.1177/096032719501400106.

Abstract
  1. Traditional remedies are an unusual, but recognised cause of lead poisoning. Only two cases have previously been reported in this country. 2. We report a series of five cases of lead poisoning due to traditional remedies in the West Midlands. All developed typical clinical features. 3. Blood lead and zinc protoporphyrin (ZPP) concentrations were elevated 2-10 times the upper limit of normal. The remedies contained up to 60% lead by weight. One also contained traces of mercury, another arsenic, and a third aluminium and tin. 4. Confirmation of the medicines as the cause of the poisoning was made in one patient by measurement of lead isotopic ratios. 5. The present morbidity from traditional remedies may be far greater than is realised, and will continue until such time as the supply of harmful preparations can be effectively limited. There needs to be increased awareness of their dangers amongst doctors and the communities at risk. This will best be achieved by appropriately targeted education.
摘要
  1. 传统药物是铅中毒一种罕见但已被认知的病因。此前该国仅报告过两例。2. 我们报告了西米德兰兹郡因传统药物导致的一系列五例铅中毒病例。所有患者均出现了典型的临床症状。3. 血铅和锌原卟啉(ZPP)浓度升高至正常上限的2至10倍。这些药物含铅量高达重量的60%。其中一种还含有微量汞,另一种含砷,第三种含铝和锡。4. 通过测量铅同位素比率,一名患者被确诊药物为中毒病因。5. 传统药物目前造成的发病率可能远高于人们的认知,在有害制剂供应得到有效限制之前还会持续。医生和高危社区需要提高对其危险性的认识。这最好通过有针对性的教育来实现。

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