Kay L, Avlund K
Medical Department C, Glostrup County Hospital, University of Copenhagen, Denmark.
Aging (Milano). 1994 Dec;6(6):420-6. doi: 10.1007/BF03324273.
Data concerning a random cohort of 1,119 70-year-old subjects were analyzed to evaluate the association between Upper Dyspepsia and Irritable Bowel Syndrome and functional ability. Seven hundred and thirty-four subjects were interviewed about abdominal symptoms and were visited at home by an occupational therapist who evaluated their functional ability. Among the survivors, 94% participated in a follow-up study five years later. Functional ability was registered on validated scales constructed for its measurement in a normal elderly population. It was found that both syndromes occurred more often among subjects with reduced functional ability. A significant association was found between the occurrence of Upper Dyspepsia and a reduction of mobility and lower limb function, and between reduced functional ability and Irritable Bowel Syndrome at the five-year follow-up. It is concluded that abdominal syndromes are associated to functional ability, suggesting that there is a diffuse disorder affecting both smooth and striated muscles.
对1119名70岁受试者的随机队列数据进行了分析，以评估上消化道消化不良与肠易激综合征之间的关联以及功能能力。734名受试者接受了腹部症状访谈，并由一名职业治疗师到家中评估他们的功能能力。在幸存者中，94%的人在五年后参与了一项随访研究。功能能力是根据为正常老年人群测量而构建的经过验证的量表进行记录的。研究发现，这两种综合征在功能能力下降的受试者中更常出现。在五年随访中，发现上消化道消化不良的发生与活动能力和下肢功能下降之间存在显著关联，以及功能能力下降与肠易激综合征之间存在显著关联。结论是腹部综合征与功能能力相关，这表明存在一种影响平滑肌和横纹肌的弥漫性疾病。
