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老年人群随机样本中胃肠道症状的患病率、发病率及预后

Prevalence, incidence and prognosis of gastrointestinal symptoms in a random sample of an elderly population.

作者信息

Kay L

机构信息

Glostrup Population Studies, Københavns Amts Sygehus i Glostrup, Denmark.

出版信息

Age Ageing. 1994 Mar;23(2):146-9. doi: 10.1093/ageing/23.2.146.

DOI:10.1093/ageing/23.2.146
PMID:8023724
Abstract

In 1984 a random sample of a 70-year-old Danish population of 1119 subjects was questioned about abdominal symptoms and 5 years later survivors were contacted for follow-up. The participation rate at the primary study was 72% and 91% of the surviving subjects attended the follow-up. One-year period prevalences of single symptoms were 1-40%, annual incidence values 1-25% and 5-year disappearance rates were more than 50%. Irritable bowel syndrome occurred with a prevalence of 6-18% depending on definition, and incidences were of a similar magnitude. At the 5-year follow-up 50-79% of subjects originally suffering from irritable bowel syndrome no longer did so. The annual prevalence rate of symptoms of upper dyspepsia varied from 9% to 25%, annual incidence was 3-12%, and cumulative 5-year disappearance rate 45-65%. It is concluded that abdominal symptoms and the syndromes they constitute occur frequently and fluctuatingly in the elderly population.

摘要

1984年,对1119名70岁丹麦人群的随机样本进行了关于腹部症状的询问,5年后对幸存者进行随访。初次研究的参与率为72%,91%的存活受试者参加了随访。单一症状的一年期患病率为1% - 40%,年发病率为1% - 25%,5年消失率超过50%。根据定义,肠易激综合征的患病率为6% - 18%,发病率也处于相似水平。在5年随访时,最初患有肠易激综合征的受试者中有50% - 79%不再患病。上消化道消化不良症状的年患病率从9%到25%不等,年发病率为3% - 12%,5年累计消失率为45% - 65%。结论是,腹部症状及其所构成的综合征在老年人群中频繁且波动地出现。

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