Talley N J, Boyce P, Jones M
Department of Medicine, University of Sydney, Australia.
Gut. 1998 May;42(5):690-5. doi: 10.1136/gut.42.5.690.
The current classification dividing patients with functional gastrointestinal symptoms into subgroups remains controversial.
To determine whether distinct symptom groupings exist in the community.
A random sample of Sydney residents in Penrith, Australia was mailed a validated self report questionnaire. Gastrointestinal symptoms including the Rome criteria for irritable bowel syndrome (IBS) and dyspepsia were measured.
Among 730 respondents, the 12 month age and gender adjusted prevalence (adjusted to the Australian population) of IBS, dyspepsia, and gastro-oesophageal reflux were 11.8% (95% confidence interval (CI) 9.3 to 14.3%), 11.5% (95% CI 9.6 to 14.6%), and 17.5% (95% CI 14.2 to 19.9%), respectively. In total, 60% of the population reported four or more gastrointestinal symptoms. There was considerable overlap of IBS with dyspepsia and among the dyspepsia subgroups by application of the Rome criteria. Independently, 10 symptom groupings were identified by factor analysis. The underlying constructs measured by these factors were generally the major abdominal syndromes recognised by the Rome classification: dyspepsia, IBS, reflux, painless constipation, painless diarrhoea, and bloating, in addition to a number of more specific symptom groupings.
Gastrointestinal symptoms are common and overlap in the community, but distinct upper and lower abdominal symptom groupings can be identified.
目前将功能性胃肠症状患者分为亚组的分类方法仍存在争议。
确定社区中是否存在不同的症状分组。
向澳大利亚彭里斯的悉尼居民随机抽样邮寄一份经过验证的自我报告问卷。测量包括肠易激综合征（IBS）和消化不良的罗马标准在内的胃肠症状。
在730名受访者中，IBS、消化不良和胃食管反流的12个月年龄和性别调整患病率（根据澳大利亚人口调整）分别为11.8%（95%置信区间（CI）9.3%至14.3%）、11.5%（95%CI 9.6%至14.6%）和17.5%（95%CI 14.2%至19.9%）。总体而言，60%的人群报告有四种或更多的胃肠症状。通过应用罗马标准，IBS与消化不良以及消化不良亚组之间存在相当大的重叠。通过因子分析独立确定了10个症状分组。这些因子测量的潜在结构通常是罗马分类认可的主要腹部综合征：消化不良、IBS、反流、无痛性便秘、无痛性腹泻和腹胀，此外还有一些更具体的症状分组。
胃肠症状在社区中很常见且相互重叠，但可以识别出明显的上腹部和下腹部症状分组。
