Ritieni A, Fogliano V, Randazzo G, Scarallo A, Logrieco A, Moretti A, Mannina L, Bottalico A
Dipartimento di Scienza degli Alimenti dell'Università degli Studi di Napoli, Federico II, Portici, Italy.
Nat Toxins. 1995;3(1):17-20. doi: 10.1002/nt.2620030105.
A new toxic sesterterpene, named fusaproliferin, was purified from corn kernel cultures (120 mg/kg dry culture) of a strain of Fusarium proliferatum isolated from corn ear rot in northern Italy. The stain, designated ITEM-1494, also produced fumonisin B1 (1.500 mg/kg dry culture) and beauvericin (90 mg/kg dry culture), but not moniliformin. To monitor toxicity, the brine shrimp assay was used throughout the isolation procedure. Fusaproliferin had a molecular formula of C27H40O5, and it is the first sesterterpene isolated from a Fusarium species.
从意大利北部玉米穗腐病分离出的一株层出镰刀菌的玉米粒培养物（120毫克/千克干培养物）中纯化出一种新的有毒倍半萜烯，命名为镰刀菌增殖素。该菌株命名为ITEM - 1494，还产生伏马毒素B1（1.500毫克/千克干培养物）和白僵菌素（90毫克/千克干培养物），但不产生串珠镰刀菌素。为监测毒性，在整个分离过程中使用了卤虫生物测定法。镰刀菌增殖素的分子式为C27H40O5，它是从镰刀菌属中分离出的首个倍半萜烯。
