古巴HIV-1分离株的包膜V3区序列。
Envelope V3 region sequences of Cuban HIV-1 isolates.
作者信息
Rolo F M, Miranda L, Wainberg M A, Gu Z, Lobaina L, Noa E, Mato J, Machado F, Martin Z
机构信息
National AIDS Research Laboratory, Havana, Cuba.
出版信息
J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Jun 1;9(2):123-5.
The origin of HIV-1 species, responsible for the AIDS epidemic in Cuba, is a subject that has been intensely debated. This study represents an initial attempt to shed light on this issue, through sequence analysis of the V3 regions of viruses isolated from 15 Cuban subjects. We now report that these viruses fall within three distinct, well-recognized groupings. These findings suggest that viruses of different sources are responsible for the HIV/AIDS epidemic in Cuba.
导致古巴艾滋病流行的HIV-1毒株的起源是一个备受激烈争论的话题。本研究通过对从15名古巴受试者身上分离出的病毒的V3区域进行序列分析，初步尝试阐明这一问题。我们现在报告，这些病毒分属于三个不同的、公认的类别。这些发现表明，不同来源的病毒导致了古巴的艾滋病毒/艾滋病流行。
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