Hillerdal G, Gustafsson G, Wegenius G, Englesson S, Hedenström H, Hedenstierna G
Department of Lung Medicine, University Hospital, Uppsala, Sweden.
Chest. 1995 May;107(5):1450-3. doi: 10.1378/chest.107.5.1450.
Five patients with poor lung function (FEV1, 0.8 to 1.0 L; MVV, 27 to 36 L/min) and large emphysematous bullae were operated on. Fibrin glue was introduced into the bullae through a thoracoscope. The results have been excellent and no serious perioperative or postoperative complications have occurred. The patients have all improved clinically and are very satisfied with the results. Postoperatively, FEV1 was between 1.0 and 1.2, and MVV was 30 to 52 L. The clinical improvement was, however, larger than these figures illustrate. Our preliminary experience using this technique suggests that it can be used in patients with very low lung function with a minimal risk. We propose that all patients with severe emphysema should be screened for bullous components because improvement might be possible by operation with this minimally traumatizing technique.
对5例肺功能较差（第一秒用力呼气容积[FEV1]为0.8至1.0升；最大通气量[MVV]为27至36升/分钟）且有巨大肺气肿性肺大疱的患者进行了手术。通过胸腔镜将纤维蛋白胶注入肺大疱。结果非常理想，未发生严重的围手术期或术后并发症。所有患者临床症状均有改善，对结果非常满意。术后，FEV1在1.0至1.2之间，MVV为30至52升。然而，临床改善程度比这些数字所显示的要大。我们使用该技术的初步经验表明，它可用于肺功能极低的患者，且风险极小。我们建议对所有重度肺气肿患者进行肺大疱成分筛查，因为采用这种微创技术进行手术可能会改善病情。
