Chaudhuri T K, Mandal T K, Sen T K, Taneja V
Department of Zoology, University of North Bengal, Siliguri.
Indian J Med Res. 1995 Apr;101:170-2.
Fifty unrelated Indian Gurkha of Nepalese origin were studied to analyse the HLA antigen profile and their relation with other populations. Haplotype B35-Cw4 occurred with highest incidence and significant positive linkage disequilibrium in Gurkhas. Haplotype A10-B8 which occurs with the highest frequency in north Indians was also observed to occur with significant positive linkage in Gurkhas. HLA profile of Gurkhas thus may be the result of long-term isolation and genetic drift.
对50名来自尼泊尔的印度廓尔喀人（彼此无亲缘关系）进行了研究，以分析其HLA抗原谱及其与其他人群的关系。单倍型B35 - Cw4在廓尔喀人中出现的频率最高，且存在显著的正连锁不平衡。在北印度人中出现频率最高的单倍型A10 - B8在廓尔喀人中也被观察到存在显著的正连锁。因此，廓尔喀人的HLA谱可能是长期隔离和遗传漂变的结果。
