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北印度印度教人群样本中HLA抗原的分布情况。

Distribution of HLA antigens in a sample of the North Indian Hindu population.

作者信息

Mehra N K, Taneja V, Kailash S, Raizada N, Vaidya M C

出版信息

Tissue Antigens. 1986 Feb;27(2):64-74. doi: 10.1111/j.1399-0039.1986.tb01500.x.

DOI:10.1111/j.1399-0039.1986.tb01500.x
PMID:3458332
Abstract

The Indian population can be divided broadly into Dravidians and the Aryans. In this report, we have attempted to analyze the HLA genetic profile of 400 native North Indian Hindus of Aryan descent. The gene frequencies of a majority of class I and II antigens show similarity to the Caucasoid population. An interesting finding was a complete lack of antigen B14 while B16 and B41 occurred with the least frequency. Haplotype A10, B8 with significant positive linkage disequilibrium as well as showing the highest incidence is characteristic of North Indians.

摘要

印度人口大致可分为达罗毗荼人和雅利安人。在本报告中,我们试图分析400名具有雅利安血统的北印度本土印度教徒的HLA基因谱。大多数I类和II类抗原的基因频率与高加索人群相似。一个有趣的发现是完全缺乏抗原B14,而B16和B41出现的频率最低。单倍型A10、B8具有显著的正连锁不平衡,且发病率最高,是北印度人的特征。

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