Felson D T
Boston University Arthritis Center, MA, USA.
J Rheumatol Suppl. 1995 Feb;43:7-9.
Overweight persons are at high risk of osteoarthritis (OA) in the knee, and probably in the hips and hands. The mechanism by which overweight causes OA is poorly understood, with a likely contribution from both local increased force across the joint and systemic factors. Better evidence is needed on the effects of weight loss, but preliminary studies suggest that weight loss can both prevent the onset of symptomatic disease and alleviate symptoms, when present.
超重人群患膝关节骨关节炎（OA）的风险很高，髋关节和手部可能也会如此。超重导致骨关节炎的机制尚不清楚，可能是关节局部受力增加和全身因素共同作用的结果。关于体重减轻的影响需要更多有力证据，但初步研究表明，体重减轻既能预防症状性疾病的发生，又能在出现症状时缓解症状。
