Antonakopoulos G N, Chapple C R, Newman J, Crocker J, Tudway D C, O'Brien J M, Considine J
Department of Histopathology, East Birmingham Hospital, England.
Arch Pathol Lab Med. 1988 Mar;112(3):275-81.
The clinicopathologic features of 17 patients with xanthogranulomatous pyelonephritis are described, together with results on a number of histochemical and immunohistochemical techniques that were used to demonstrate the variety of cells involved. Based on our clinicopathologic data and review of the literature, we believe that xanthogranulomatous pyelonephritis should be regarded as a destructive, and, at times, tumefactive inflammatory process that may complicate chronic pyelonephritis. The initiation of this process remains an enigma. However, there appears to be three main features that are associated with xanthogranulomatous pyelonephritis: pelvicalyceal obstruction, ulceration of the pelvicalyceal urothelium, and bacterial infection.
本文描述了17例黄色肉芽肿性肾盂肾炎患者的临床病理特征，以及一系列用于显示所涉及的多种细胞的组织化学和免疫组织化学技术的结果。基于我们的临床病理数据和文献回顾，我们认为黄色肉芽肿性肾盂肾炎应被视为一种破坏性的、有时呈肿块样的炎症过程，可能并发于慢性肾盂肾炎。这一过程的起始仍不明朗。然而，黄色肉芽肿性肾盂肾炎似乎有三个主要相关特征：肾盂肾盏梗阻、肾盂肾盏尿路上皮溃疡和细菌感染。
