Patrignelli R, Sheikh S H, Shaw-Stiffel T A
Department of Medicine, Bridgeport Hospital, CT 06610, USA.
Postgrad Med. 1995 May;97(5):123-4, 127, 131-4.
Henoch-Schönlein purpura is a common vasculitic syndrome of childhood that is also seen in adults. It is characterized by the deposition of immune complexes, mainly IgA and C3, in various organ systems. Diagnosis is based on the presence of nonthrombocytopenic purpura, arthritis or arthralgia, abdominal pain that may be complicated by intussusception, and glomerulonephritis. The disease is usually self-limited and lasts a few weeks but may recur. Recovery is complete in almost all patients, with the severity of renal involvement dictating any remaining sequelae. Corticosteroid therapy may provide acute symptomatic relief but apparently has no effect on the natural course of the disease.
过敏性紫癜是一种常见的儿童血管炎综合征，在成人中也可见。其特征是免疫复合物（主要是IgA和C3）在各种器官系统中沉积。诊断基于非血小板减少性紫癜、关节炎或关节痛、可能并发肠套叠的腹痛以及肾小球肾炎的存在。该疾病通常为自限性，持续数周，但可能复发。几乎所有患者均可完全康复，肾脏受累的严重程度决定了任何残留的后遗症。皮质类固醇疗法可能会提供急性症状缓解，但显然对疾病的自然病程没有影响。
