Smolle J, Rieger E, Hödl S, Kerl H
Universitätsklinik für Dermatologie und Venerologie, Graz.
Ther Umsch. 1995 Apr;52(4):251-6.
In neoplastic diseases of the haemopoietic and the lymphatic system, the skin may be infiltrated specifically by neoplastic cells or may display 'nonspecific' cutaneous reactions, frequently associated with a systemic malignancy. Acute febrile neutrophilic dermatosis associated with myeloproliferative disorders and scleromyxedema, lichen myxedematosus, diffuse plane xanthomas and necrobiotic xanthogranuloma associated with paraproteinemia may serve as examples. These conditions as well as several other, often atypical cutaneous manifestations should rise suspicion as to the potential presence of some underlying systemic neoplastic disorder.
在造血系统和淋巴系统的肿瘤性疾病中，皮肤可能会被肿瘤细胞特异性浸润，或表现出“非特异性”皮肤反应，这些反应常与全身恶性肿瘤相关。与骨髓增殖性疾病相关的急性发热性嗜中性皮病、硬化性黏液水肿、黏液性苔藓、弥漫性扁平黄瘤以及与副蛋白血症相关的渐进性坏死性黄色肉芽肿都可作为例子。这些情况以及其他几种往往不典型的皮肤表现，应引起对潜在存在某些潜在全身性肿瘤性疾病的怀疑。
