Posadas G, Vaquero J, Herrero J, Bravo G
Neurosurgery Service, Universidad Autónoma de Madrid, Spain.
Acta Neurochir (Wien). 1994;131(3-4):189-95. doi: 10.1007/BF01808611.
The purpose of the present retrospective study is to analyse 14 patients harbouring brainstem haematomas and to discuss the early and late prognosis. The patients were divided into two groups: group A (survivors), 8 patients with follow-up duration ranging between 8 months and 12 years; and group B (nonsurvivors), 6 patients. At the time of onset or hospital admission, the former were under 50 years of age and had no important clinical history. Their degree of consciousness was altered only slightly or moderately and their brainstem haemorrhages were focal or only slightly diffuse. Three patients in this group underwent surgical treatment. The members of group B, who died within days of their admission to the hospital, were over 60 years of age, had a number of clinical antecedents and severe alterations of consciousness, while 83% of them presented diffuse brainstem haemorrhages. None of the patients of this group were treated surgically. It was concluded that: 1) the indications for surgery for these lesions were progressive hydrocephalus, increase in the mass effect with progressive symptomatology and suspected "cryptic vascular malformation" with risk of later rebleeding or brain tumour; 2) surgical treatment was necessary to improve the symptomatology in 3 patients in group A, although there were no significant differences between surgically treated and nonsurgically treated patients in the same group with respect to prognosis; 3) age, clinical history, degree of alteration of consciousness and type of haemorrhage are the major factors affecting the early and late prognosis of brainstem haemorrhages.
本回顾性研究的目的是分析14例脑干血肿患者,并探讨其早期和晚期预后。患者分为两组:A组(幸存者),8例,随访时间为8个月至12年;B组(非幸存者),6例。发病时或入院时,A组患者年龄在50岁以下,无重要临床病史。其意识障碍仅为轻度或中度,脑干出血为局灶性或仅轻度弥漫性。该组3例患者接受了手术治疗。B组患者入院数天内死亡,年龄超过60岁,有多种临床既往史且意识严重障碍,其中83%表现为弥漫性脑干出血。该组患者均未接受手术治疗。得出以下结论:1)这些病变的手术指征为进行性脑积水、伴有进行性症状的占位效应增加以及疑似有后期再出血风险的“隐匿性血管畸形”或脑肿瘤;2)手术治疗对改善A组3例患者的症状是必要的,尽管在同一组中,手术治疗和非手术治疗患者的预后无显著差异;3)年龄、临床病史、意识障碍程度和出血类型是影响脑干出血早期和晚期预后的主要因素。