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老年患者颈椎显微外科手术。第2部分:恶性肿瘤疾病的手术治疗。

Microsurgery of the cervical spine in elderly patients. Part 2: Surgery of malignant tumourous disease.

作者信息

Seifert V, van Krieken F M, Bao S D, Stolke D, Zimmermann M

机构信息

Neurosurgical Clinic, University of Essen, Federal Republic of Germany.

出版信息

Acta Neurochir (Wien). 1994;131(3-4):241-6. doi: 10.1007/BF01808621.

DOI:10.1007/BF01808621
PMID:7754829
Abstract

In this retrospective study, the results of surgery were examined in 25 patients, 65 years of age or older, suffering from malignant tumour growth along the cervical spine. The group consisted of 17 men and 8 women. The mean age was 73 years, ranging from 66 to 88 years. The pathology identified was metastasis in 23 patients, and plasmocytoma in two. The tumour localization involved a single segment of the cervical spine in 12 patients, two segments in 8 patients, three segments in 4 patients, and four segments in one patient. Pre-operatively, 8 patients (32%) suffered solely from severe pain. 6 patients (24%) showed severe pain and radicular nerve compression. 5 patients (20%) had incomplete para- or tetraparesis but were able to walk, and again 6 patients (24%) had incomplete para- or tetraparesis, and were unable to walk. A multitude of accompanying systemic diseases was present in the majority of patients. Evaluation of the peri-operative risk profile was performed using the American Society of Anaesthesiology (ASA) Grading of Physical Status Score. Operation consisted of microsurgical tumour removal, usually incorporating a single- or multi-level vertebrectomy, with radical epidural decompression, and grafting with bone cement followed by an appropriate osteosynthesis. Of the whole cohort of patients treated, four patients were still alive at the time of the last follow-up evaluation. 21 patients died. Four patients died within seven days after surgery. The remaining 17 patients died during the follow-up period. All of these patients died from systemic spread of their primary cancer.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

在这项回顾性研究中,对25例65岁及以上患有颈椎恶性肿瘤生长的患者的手术结果进行了检查。该组包括17名男性和8名女性。平均年龄为73岁,范围在66至88岁之间。病理检查发现23例为转移瘤,2例为浆细胞瘤。肿瘤定位涉及颈椎单节段的患者有12例,两个节段的有8例,三个节段的有4例,四个节段的有1例。术前,8例患者(32%)仅患有严重疼痛。6例患者(24%)表现为严重疼痛和神经根受压。5例患者(20%)有不完全性截瘫或四肢瘫但能够行走,另有6例患者(24%)有不完全性截瘫或四肢瘫且无法行走。大多数患者存在多种伴随的全身性疾病。使用美国麻醉医师协会(ASA)身体状况评分分级对围手术期风险状况进行评估。手术包括显微手术切除肿瘤,通常包括单节段或多节段椎体切除术、彻底的硬膜外减压、骨水泥植骨,随后进行适当的骨固定。在接受治疗的整个患者队列中,在最后一次随访评估时,有4例患者仍存活。21例患者死亡。4例患者在术后7天内死亡。其余17例患者在随访期间死亡。所有这些患者均死于原发癌的全身扩散。(摘要截取自250字)

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本文引用的文献

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Spondylectomy, microsurgical decompression and osteosynthesis in the treatment of complex disorders of the cervical spine.颈椎复杂疾病治疗中的椎体切除术、显微手术减压及骨固定术
Acta Neurochir (Wien). 1993;124(2-4):104-13. doi: 10.1007/BF01401131.
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Spine (Phila Pa 1976). 1989 Oct;14(10):1071-7. doi: 10.1097/00007632-198910000-00008.