Seifert V, van Krieken F M, Zimmermann M, Stolke D, Bao S D
Neurosurgical Clinic, University of Essen, Federal Republic of Germany.
Acta Neurochir (Wien). 1994;131(1-2):119-24. doi: 10.1007/BF01401461.
The results of microsurgery for degenerative disease of the cervical spine are reported in 84 consecutive patients being 65 years of age or older at the time of surgery. Patients were suffering from either soft or hard disc disease or from advanced forms of cervical myelopathy. In 60 patients microsurgical resection of the involved cervical disc and posterior osteophytes was performed followed by anterior fusion. Spondylectomy, microsurgical decompression and osteosynthesis was performed in 24 patients with multi-level cervical stenosis. A multitude of accompanying systemic diseases was present in almost all patients. Evaluation of the peri-operative risk profile of the patients was performed using the American Society of Anesthesiology (ASA) Grading of Physical Status Score. In 82 patients a complete follow-up was available. Two patients died within seven days after surgery from heart attack and pulmonary embolism. Three patients died during the observation period from causes unrelated to their cervical disease or to surgery. Overall surgical results were as follows: 66 patients (79%) were improved by surgery, 14 patients (17%) were unchanged, two patients (2%) became worse, and two patients (2%) died. Postoperative recovery was significantly correlated to the pre-operative neurological status. Neither age, nor the pre-operative ASA score had a significant influence on the postoperative outcome. The incidence of peri-operative systemic complications was significantly correlated to the pre-operative physical status of the patients according to the ASA score. No significant correlation towards an increase of peri-operative complications with higher grades of pre-operative neurological deficits or with increasing age of the patients could be found.(ABSTRACT TRUNCATED AT 250 WORDS)
报告了84例65岁及以上颈椎退行性疾病患者的显微手术结果。这些患者患有软性或硬性椎间盘疾病或晚期颈椎病。60例患者进行了受累颈椎间盘和后骨赘的显微手术切除,随后进行前路融合术。24例多节段颈椎管狭窄患者进行了椎体切除术、显微手术减压和骨合成术。几乎所有患者都存在多种伴随的全身性疾病。使用美国麻醉医师协会(ASA)身体状况评分对患者的围手术期风险状况进行评估。82例患者获得了完整的随访。2例患者术后7天内死于心脏病发作和肺栓塞。3例患者在观察期内死于与颈椎疾病或手术无关的原因。总体手术结果如下:66例患者(79%)手术改善,14例患者(17%)无变化,2例患者(2%)病情恶化,2例患者(2%)死亡。术后恢复与术前神经状态显著相关。年龄和术前ASA评分对术后结果均无显著影响。根据ASA评分,围手术期全身并发症的发生率与患者术前身体状况显著相关。未发现术前神经功能缺损程度较高或患者年龄增加与围手术期并发症增加之间存在显著相关性。(摘要截断于250字)