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Metabolic activation: biochemical basis for many drug-induced liver injuries.

作者信息

Mitchell J R, Nelson S D, Thorgeirsson S S, McMurtry R J, Dybing E

出版信息

Prog Liver Dis. 1976;5:259-79.

PMID:775543
Abstract
摘要

相似文献

1
Metabolic activation: biochemical basis for many drug-induced liver injuries.代谢活化：许多药物性肝损伤的生化基础。
Prog Liver Dis. 1976;5:259-79.
2
Drug metabolism in the production of liver injury.
Med Clin North Am. 1975 Jul;59(4):877-85. doi: 10.1016/s0025-7125(16)31986-1.
3
[Drug induced liver injury. Chemical liver necrosis caused by formation of reactive metabolites].[药物性肝损伤。由反应性代谢产物形成导致的化学性肝坏死]
Tidsskr Nor Laegeforen. 1976 Feb 10;96(4):220-1.
4
[Reactive metabolites of xenobiotics : their role in the hepatotoxicity of drugs].[外源性物质的反应性代谢产物：它们在药物肝毒性中的作用]
C R Seances Soc Biol Fil. 1979;173(2):458-68.
5
Drug-induced liver injury.药物性肝损伤
Hosp Pract. 1978 Sep;13(9):95-8, 103-4, 106. doi: 10.1080/21548331.1978.11707401.
6
The role of metabolic activation for drug-induced liver injuries.代谢活化在药物性肝损伤中的作用。
Acta Pharmacol Toxicol (Copenh). 1977;41 Suppl 2:263-72.
7
[Intermediate metabolites and liver toxicity].[中间代谢产物与肝脏毒性]
Nihon Rinsho. 1985 Jun;43(6):1127-33.
8
Potential environmental chemical hazards. I. Drugs.潜在的环境化学危害。一、药物。
Sci Total Environ. 1972 May;1(1):15-30. doi: 10.1016/0048-9697(72)90010-1.
9
Drug-induced liver injury.药物性肝损伤
Neth J Med. 1980;23(1):23-32.
10
[Drug-induced liver damage; new aspects on its mechanism].[药物性肝损伤；其机制的新进展]
Duodecim. 1980;96(5):394-402.

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Analysis of the relationship between liver regeneration rate and blood levels.肝再生率与血液水平之间关系的分析。
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6
Fluorescence-microscopic measurement of intracellular cytochrome P-450 enzyme activity (ethoxyresorufin O-de-ethylation) in unfixed liver section.在未固定的肝脏切片中进行细胞色素P-450酶活性（乙氧试卤灵O-脱乙基化）的荧光显微镜测量。
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A comparison of hepatocyte size distribution in untreated and phenobarbital-treated rats as assessed by flow cytometry.通过流式细胞术评估未处理和苯巴比妥处理大鼠肝细胞大小分布的比较。
Dig Dis Sci. 1984 Aug;29(8):753-7. doi: 10.1007/BF01312949.
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Toxicity of polybrominated biphenyls (PBBs) in Domestic and laboratory animals.多溴联苯（PBBs）对家畜和实验动物的毒性
Environ Health Perspect. 1982 Apr;44:175-88. doi: 10.1289/ehp.8244175.
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Interplay of factors leading to adverse drug reactions in the liver, a personal viewpoint.导致肝脏药物不良反应的因素之间的相互作用：个人观点
Yale J Biol Med. 1977 Sep-Oct;50(5):489-95.
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Hepatic injury and drug metabolism in patients with alpha-methyldopa-induced liver damage.α-甲基多巴所致肝损伤患者的肝损伤与药物代谢
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