Tsuang J W, Irwin M R, Smith T L, Schuckit M A
San Diego Veterans Affairs Medical Center, California 92161.
Addiction. 1994 Jan;89(1):73-8. doi: 10.1111/j.1360-0443.1994.tb00851.x.
The goal of this study was to evaluate the characteristics of primary alcoholics with alcoholic hallucinosis. Six hundred and forty-three primary alcoholic men were recruited from a 28-day Alcohol and Drug Treatment Program at the San Diego VA Medical Center. Subjects only experiencing perceptual abnormalities during alcohol withdrawal, drug-related hallucinosis, as well as those having abnormal sensations that did not meet criteria for hallucinations were excluded from the present study. The remaining 532 subjects were divided into Group 1 (n = 48), which consisted of subjects with a DSM-IIIR and ICD-10 diagnosis of alcoholic hallucinosis, and Group 2 (n = 484) which consisted of those without any history of hallucinations. A comparison of the two groups revealed that Group 1 men were younger at the onset of alcohol problems, consumed more alcohol per occasion, developed more alcohol-related life problems, and had higher rates of drug experimentation as well as more different types of drugs used. This study suggests that primary alcoholics who consume more drugs and/or alcohol might be at an increased risk for developing alcoholic hallucinosis.
本研究的目的是评估患有酒精性幻觉症的原发性酗酒者的特征。从圣地亚哥退伍军人事务医疗中心为期28天的酒精和药物治疗项目中招募了643名原发性酗酒男性。本研究排除了仅在酒精戒断期间出现感知异常、与药物相关的幻觉症以及有不符合幻觉标准的异常感觉的受试者。其余532名受试者被分为第1组(n = 48),该组由患有DSM-IIIR和ICD-10酒精性幻觉症诊断的受试者组成,以及第2组(n = 484),该组由没有任何幻觉病史的受试者组成。两组比较显示,第1组男性在出现酒精问题时更年轻,每次饮酒量更多,出现更多与酒精相关的生活问题,药物试验率更高,使用的药物类型也更多。这项研究表明,服用更多药物和/或酒精的原发性酗酒者可能患酒精性幻觉症的风险增加。