Flaitz C M, Nichols C M, Hicks M J
Division of Oral Pathology, University of Texas Health Science Center, Dental Branch, Houston, USA.
Compend Contin Educ Dent. 1995 Feb;16(2):136-8, 140, 142 passim; quiz 148.
Acquired immunodeficiency syndrome-associated Kaposi's sarcoma (AIDS-KS) is the most common malignancy in human immunodeficiency virus infection and is seen most often in homosexual men. The oral cavity is frequently involved by AIDS-KS and may represent the initial site of this malignancy in up to 60% of patients. A number of treatment modalities, including systemic and localized chemotherapy and radiotherapy, are available for AIDS-KS. The initial diagnosis of AIDS-KS requires microscopic evaluation of biopsy material because this disease can mimic a number of intraoral lesions, including atrophic candidiasis, erythroplakia, pyogenic granuloma, bacillary angiomatosis, median rhomboid glossitis, hemangioma, and lymphoma. Overall, treatment of AIDS-KS does not significantly affect the prognosis or survival of AIDS patients, however, treatment can alleviate aerodigestive and/or respiratory dysfunction, allow for adequate nutritional intake, and improve the quality of life for these patients.
获得性免疫缺陷综合征相关的卡波西肉瘤（AIDS-KS）是人类免疫缺陷病毒感染中最常见的恶性肿瘤，多见于同性恋男性。口腔常受累于AIDS-KS，在高达60%的患者中可能是这种恶性肿瘤的初始部位。AIDS-KS有多种治疗方式，包括全身和局部化疗以及放疗。AIDS-KS的初步诊断需要对活检材料进行显微镜评估，因为这种疾病可模仿多种口腔内病变，包括萎缩性念珠菌病、红斑、化脓性肉芽肿、杆菌性血管瘤、正中菱形舌炎、血管瘤和淋巴瘤。总体而言，AIDS-KS的治疗对艾滋病患者的预后或生存没有显著影响，然而，治疗可以缓解气消化道和/或呼吸功能障碍，保证充足的营养摄入，并改善这些患者的生活质量。
