Negro P, Gossetti F, La Pinta M, Mariani P, Carboni M
Polyclinic Umberto I, University La Sapienza, Rome, Italy.
Drugs Exp Clin Res. 1994;20(6):257-62.
The goal of the present study was to evaluate the effect of L-carnitine on plasma glucose and insulin levels. Two parallel studies were set-up, of 40 and 20 healthy volunteers, respectively. Each group received 500 cc of 10% glucose or 5% glucose, to which were randomly added 4 g or 2 g of L-carnitine and administered a week apart. Results showed that L-carnitine was able to reduce the increase in glucose plasma levels induced by infusion of the glucose solution. This finding was not dependent on an insulin-dependent mechanism.
本研究的目的是评估左旋肉碱对血糖和胰岛素水平的影响。设立了两项平行研究，分别有40名和20名健康志愿者。每组接受500毫升10%葡萄糖或5%葡萄糖，其中随机添加4克或2克左旋肉碱，并相隔一周给药。结果表明，左旋肉碱能够降低输注葡萄糖溶液引起的血糖水平升高。这一发现不依赖于胰岛素依赖机制。
