Tatarko S V, Klymenko M O
Fiziol Zh (1994). 1995 Sep-Dec;41(5-6):103-6.
On the model of peritonitis induced by E. coli in rats the regularities of repair in dynamics of acute infectious inflammation and post-inflammatory regeneration have been studied. The peaks of neutrophils, macrophages, immature fibroblasts and restoration of mature fibroblasts number in mesenterium on the 1, 3, 5, and 10th days, respectively, have been found. The synthetic functional activity of macrophages and fibroblasts reached their peaks in the same terms. The increased activities of macrophages up to the 90th day, immature fibroblasts up to the 30-60th day and mature fibroblasts up to the 60-90th day have been marked.
以大鼠大肠杆菌诱导的腹膜炎模型,研究了急性感染性炎症和炎症后再生动态过程中的修复规律。分别在第1、3、5和10天发现了中性粒细胞、巨噬细胞、未成熟成纤维细胞数量的峰值以及肠系膜中成熟成纤维细胞数量的恢复情况。巨噬细胞和成纤维细胞的合成功能活性在相同时间达到峰值。巨噬细胞的活性在第90天前增加,未成熟成纤维细胞在第30 - 60天增加,成熟成纤维细胞在第60 - 90天增加。