Menghetti E, Mucedola G, Montaleone M, Marulli P
Istituto di Puericultura, Università degli Studi, La Sapienza, di Roma.
Riv Eur Sci Med Farmacol. 1993 May-Aug;15(3-4):159-62.
Two groups of healthy children, born on time, have been studied: 96 affected by familiarity with arterial hypertension and 105 not affected. Each baby has been recorded sex, weight, height, and the type of delivery. During their first three days of life the babies have been subjected to monitoring of the arterial pressure through an automatic oscillometric Air Shields apparatus with a 3.5 cm height bangle. We have recorded the systolic pressure, the medium, the diastolic and the heart frequency for 15 minutes in succession with 1 minute intervals, during daily hours. The babies of the two groups have shown in percentage a superimposable average weight, height, sex and the type of delivery. Even the arterial pressure, either systolic or diastolic, and the heart frequency have not shown significant differences. On the contrary the cases of hypertension (systolic pressure higher than 90 mmHg) within the two groups have shown significant statistic differences with a larger number of picks of hypertension among babies with familiarity, to indicate a greater unsteadiness of the pressure among them. Also the number of the scanned subjects affected by hypertension is significantly and statistically greater among babies with relatives who have been affected by hypertension. In conclusion the familiarity with arterial hypertension "affects" already at the neonatal age.
96名有动脉高血压家族史，105名无家族史。记录了每个婴儿的性别、体重、身高和分娩方式。在出生后的头三天，通过自动示波法的Air Shields仪器（使用3.5厘米高的腕带）对婴儿的动脉血压进行监测。在每天的特定时段，以1分钟的间隔连续记录15分钟的收缩压、平均压、舒张压和心率。两组婴儿在平均体重、身高、性别和分娩方式的百分比方面表现出可叠加性。甚至收缩压或舒张压以及心率也没有显示出显著差异。相反，两组中的高血压病例（收缩压高于90 mmHg）显示出显著的统计学差异，有家族史的婴儿中高血压发作次数更多，表明他们的血压更不稳定。在有高血压亲属的婴儿中，受高血压影响的扫描对象数量在统计学上也显著更多。总之，动脉高血压家族史在新生儿期就已经产生“影响”。
