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鼻黏膜纤毛传输与扫描电子显微镜检查的相关性

The correlation of mucociliary transport and scanning electron microscopy of nasal mucosa.

作者信息

Toskala E, Nuutinen J, Rautiainen M, Torkkeli T

机构信息

Department of Otorhinolaryngology, Kuopio University, Hospital Kuopio, Finland.

出版信息

Acta Otolaryngol. 1995 Jan;115(1):61-5. doi: 10.3109/00016489509133348.

DOI:10.3109/00016489509133348
PMID:7762387
Abstract

The ciliary ultrastructure studied by scanning electron microscopy (SEM), nasal mucociliary transport rate (MTR) measured by a radioisotopic method and their correlation with each other were studied in 56 patients with recurrent or chronic respiratory infections. Patients were divided into three groups according to MTR. The number of pathological SEM findings increased remarkably in groups with moderate or poor MTR. Loss of ciliated cells and microvilli were seen in 86% of specimens with poor MTR, in 71% with moderate MTR, and in 50% with good MTR. There was ciliary disorientation in 45% of cases with poor MTR compared with 25% in cases with good MTR. Epithelial metaplasia and the number of short cilia increased in groups with poor or moderate MTR.

摘要

对56例复发性或慢性呼吸道感染患者进行了扫描电子显微镜(SEM)研究的睫状体超微结构、放射性同位素法测量的鼻黏膜纤毛传输率(MTR)及其相互关系的研究。根据MTR将患者分为三组。MTR中等或较差组的病理SEM结果数量显著增加。MTR较差的标本中86%可见纤毛细胞和微绒毛缺失,MTR中等的标本中71%可见,MTR良好的标本中50%可见。MTR较差的病例中有45%出现睫状体排列紊乱,而MTR良好的病例中为25%。MTR较差或中等组的上皮化生和短纤毛数量增加。

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