Menditto A, Ouane-Keita F, Chiodo F, Caroli S
Laboratorio di Biochimica Clinica, Istituto Superiore di Sanità, Rome, Italy.
Ann Ist Super Sanita. 1994;30(4):425-31.
Although chemicals provide important benefits, they can also represent hazards to human health or the environment. However, due to number of chemicals involved, clearly no country can deal alone with the evaluation of existing scientific, technical and legal information on chemicals. This implies a need for countries to work together to assess the risk posed by chemicals and to share the results in a compatible and understandable way. In 1973 the governing council of United Nations Environment Programme (UNEP) decided to proceed with the creation of the International Register of Potentially Toxic Chemicals (IRPTC). The core activity of IRPTC is the collection of information on chemicals into a computerized data bank and the dissemination of these data in the form of chemical data profiles. The data profiles focus on selected chemicals with a potential to affect human health and the environment, excluding chemicals whose sole use is as a pharmaceutical or which are radioactive substances. The data collection and selection activities of IRPTC are driven by two key issues: data quality and data quantity. The objective of IRPTC in this respect is to provide decision-makers and other users with the most pertinent data available to substantiate their assessment of hazard. Providing reliable and detailed data in manageable amounts was the strategy chosen to achieve this objective.(ABSTRACT TRUNCATED AT 250 WORDS)
尽管化学品带来了重要益处，但它们也可能对人类健康或环境构成危害。然而，由于涉及的化学品数量众多，显然没有哪个国家能够独自应对对现有化学品科学、技术和法律信息的评估。这意味着各国需要共同努力，评估化学品所构成的风险，并以兼容且易懂的方式分享结果。1973年，联合国环境规划署（UNEP）理事会决定着手创建国际潜在有毒化学品登记册（IRPTC）。IRPTC的核心活动是将化学品信息收集到计算机化数据库中，并以化学数据档案的形式传播这些数据。数据档案聚焦于可能影响人类健康和环境的特定化学品，不包括仅用作药品或为放射性物质的化学品。IRPTC的数据收集和筛选活动由两个关键问题驱动：数据质量和数据数量。在这方面，IRPTC的目标是为决策者和其他用户提供最相关的数据，以证实他们对危害的评估。提供数量可控的可靠且详细的数据是实现这一目标所选择的策略。（摘要截取自250词）
