大叶报春皂苷，一种来自大叶报春的皂苷。

Macrophyllicin, a saponin from Primula macrophylla.

作者信息

Ahmad V U, Shah M G, Mohammad F V, Baqai F T

机构信息

H.E.J. Research Institute of Chemistry, University of Karachi, Pakistan.

出版信息

Phytochemistry. 1993 Apr;32(6):1543-7. doi: 10.1016/0031-9422(93)85176-r.

DOI:10.1016/0031-9422(93)85176-r

PMID:7763557

Abstract

A new triterpenoid saponin, macrophyllicin has been isolated from the methanolic extract of the whole plant of Primula macrophylla. On the basis of chemical and spectral evidence, the structure of macrophyllicin was determined as 3-O-[alpha-L-rhamnopyranosyl-(1-->2)-beta-D-glucopyranosyl- (1-->2)-beta-D-galactopyranosyl-(1-->2)-beta-D-glucuronopyranosyl] -6 beta,16 alpha,28-trihydroxy-olean-12-ene. The 2D NMR experiments were useful in providing complete information on the structure of macrophyllogenin, a new sapogenin.

摘要

从大叶报春花全草的甲醇提取物中分离出一种新的三萜皂苷——大叶报春花苷。基于化学和光谱证据，确定大叶报春花苷的结构为3 - O - [α - L - 鼠李吡喃糖基 - (1→2) - β - D - 吡喃葡萄糖基 - (1→2) - β - D - 吡喃半乳糖基 - (1→2) - β - D - 葡萄糖醛酸吡喃糖基] - 6β,16α,28 - 三羟基 - 齐墩果 - 12 - 烯。二维核磁共振实验有助于提供有关一种新皂苷元——大叶报春花苷元结构的完整信息。