Buckholz R G
Biotechnology Department, Glaxo Research Institute, Research Triangle Park, North Carolina 27709.
Curr Opin Biotechnol. 1993 Oct;4(5):538-42. doi: 10.1016/0958-1669(93)90074-7.
Significant advances have been made over the past year in our understanding of some of the critical parameters affecting high-level production of heterologous proteins in yeast. Recent studies of plasmid stability, promoter strength and secretion efficiency are yielding potential improvements in expression.
在过去一年里，我们对影响酵母中异源蛋白高水平生产的一些关键参数的理解取得了重大进展。最近关于质粒稳定性、启动子强度和分泌效率的研究正在为表达带来潜在的改进。
