Nkengfack A E, Vouffo T W, Fomum Z T, Meyer M, Bergendorff O, Sterner O
Department of Organic Chemistry, University of Yaounde I, Cameroon.
Phytochemistry. 1994 Jul;36(4):1047-51. doi: 10.1016/s0031-9422(00)90489-8.
A novel prenylated isoflavanone, sigmoidin I, has been isolated from the roots of Erythrina sigmoidea, in addition to the known isoflavones, corylin and neobavaisoflavone and the known pterocarpan, phaseollidin. Its structure was established as 7,4'-dihydroxy-3'-methoxy-5'-(3-methylbut-2-enyl) isoflavanone by means of spectroscopic analyses and chemical transformations. Neobavaisoflavone displayed antifungal potency in vitro with minimum inhibitory concentrations against Aspergillus fumigatus and Cryptococcus neoformans, of 50 mg ml-1.
除了已知的异黄酮类化合物紫铆因和新补骨脂异黄酮以及已知的紫檀烷类化合物菜豆亭外，还从弯果刺桐根中分离出一种新型的异戊烯基化异黄酮——乙状结肠素I。通过光谱分析和化学转化确定其结构为7,4'-二羟基-3'-甲氧基-5'-(3-甲基丁-2-烯基)异黄酮。新补骨脂异黄酮在体外具有抗真菌活性，对烟曲霉和新型隐球菌的最低抑菌浓度为50毫克/毫升。
