刺毛刺桐中的异戊烯基化异黄酮

Prenylated isoflavanone from Erythrina eriotricha.

作者信息

Nkengfack A E, Vardamides J C, Fomum Z T, Meyer M

机构信息

Department of Organic Chemistry, University of Yaounde, Cameroon.

出版信息

Phytochemistry. 1995 Dec;40(6):1803-8. doi: 10.1016/0031-9422(95)00037-8.

DOI:10.1016/0031-9422(95)00037-8

PMID:8590641

Abstract

Bioassay-directed fractionation of a methylene chloride extract of the root bark of Erythrina eriotricha resulted in the isolation of a novel isoflavanone, named eriotrichin B, and the five known pterocarpans, isonorautenol, erybraedin A, erybraedin C, erybraedin D and erybraedin E. The structure of the new compound has been investigated by extensive spectroscopic studies, including 2D NMR and chemical evidence. The in vitro antimicrobial spectrum and potencies of the isolated compounds are also reported.

摘要

对刺桐根皮的二氯甲烷提取物进行生物测定导向的分级分离，得到了一种名为刺桐素B的新型异黄酮和五种已知的紫檀烷类化合物，即异去甲奥替诺醇、刺桐素A、刺桐素C、刺桐素D和刺桐素E。通过广泛的光谱研究，包括二维核磁共振和化学证据，对新化合物的结构进行了研究。还报道了分离出的化合物的体外抗菌谱和效力。