Högstedt P, Kadefors R, Näslund P E
Lindholmen Development, Gothenburg, Sweden.
Technol Health Care. 1995 Mar;3(1):15-21.
Magnetopneumography (MPG) is a non-invasive technique to measure the amount of magnetizable dust retained in the lung. This study concerns the relation between MPG measurements of welding fume dust retention in the human lung on the one hand and chest radiography and crude counting of exposure time on the other. Precision and accuracy of the MPG instrument was found to be high. A weak but statistically significant correlation (r = 0.45, P < 0.05) was found between exposure time and retention of magnetizable material in a group of 112 full time manual metal arc welders. The variability was high. Retention rate was estimated on a group level. Chest radiographs of 23 arc welders were reviewed separately in random order by two independent readers who were not aware of MPG findings, occupational anamnesis or the subject's identity and age. No statistically significant correlation was found between MPG and the observer's grading. A weak but statistically significant correlation was found between the readers. We conclude that MPG is highly sensitive to retention of magnetizable material retained in the lung and that the correlation between radiography and MPG reported by previous workers could not be verified in this study. The divergent results may well be due to methodological differences. Investigations using more specific roentgenological methods, such as high resolution computed tomography (HRCT), should be performed.
磁肺成像（MPG）是一种用于测量肺部留存的可磁化粉尘量的非侵入性技术。本研究一方面关注人体肺部焊接烟尘留存的MPG测量值与胸部X线摄影及粗略计算暴露时间之间的关系。结果发现MPG仪器的精密度和准确度都很高。在一组112名全职手工金属电弧焊工中，发现暴露时间与可磁化物质的留存之间存在微弱但具有统计学意义的相关性（r = 0.45，P < 0.05）。变异性很高。留存率是在群体水平上进行估算的。23名电弧焊工的胸部X线片由两名独立阅片者以随机顺序分别进行复查，这两名阅片者并不知晓MPG检查结果、职业病史或受检者的身份及年龄。未发现MPG与阅片者分级之间存在统计学意义的相关性。在阅片者之间发现了微弱但具有统计学意义的相关性。我们得出结论，MPG对肺部留存的可磁化物质高度敏感，且本研究未能证实先前研究者所报告的X线摄影与MPG之间的相关性。结果存在差异很可能是由于方法学上的不同。应采用更具特异性的放射学方法，如高分辨率计算机断层扫描（HRCT）进行研究。
