Pokan R, Hofmann P, Lehmann M, Leitner H, Eber B, Gasser R, Schwaberger G, Schmid P, Keul J, Klein W
Department of Internal Medicine, Karl-Franzens-University, Graz, Austria.
Eur J Appl Physiol Occup Physiol. 1995;70(2):175-9. doi: 10.1007/BF00361546.
The correlation between the behaviour of the heart rate/work performance (fc/W) curve and blood lactate ([la]b) and plasma adrenaline/noradrenaline concentrations ([A]/[NA]) during incremental cycle ergometer exercise was investigated. A group of 21 male sports students was divided into two groups: group I, with a clear deflection of the fc/W curve; group II, without or with an inverse deflection of the fc/W curve. The aerobic threshold (Thaer) and the lactate turn point (LTP) were defined. Between Thaer and maximal work performance (Wmax) the behaviour of the fc/W curve as well as the behaviour of [la-]b and [A]. [NA] were described mathematically. The fc, systolic blood pressure (BPs), W, [la-]b, [A] and [NA] at rest, Thaer, LTP, Wmax, after 3 and 6 min of recovery (Re3/Re6) were calculated. A significant difference between the two groups could only be detected for fc at LTP, Re3 and Re6 (P < 0.05). No significant correlation could be found between individual fc/W-behaviour and individual time course of [la-]b, [A] and [NA]. However, a significant correlation was visible between [la-]b/W-behaviour and individual catecholamine response. These results and the fact that the different flattening at the top of the fc/W curve was related to diminished stress-dependent myocardial function led us to the conclusion that it is possible that sympathetic drive is not directly involved in mechanisms of regulation between load dependent fc and myocardial function. In addition, individual fc/W behaviour was independent of BPs and Wmax, or individual conditions of energy supply.
研究了递增式蹬车运动期间心率/工作负荷（fc/W）曲线行为与血乳酸（[la]b）以及血浆肾上腺素/去甲肾上腺素浓度（[A]/[NA]）之间的相关性。21名男性体育专业学生被分为两组：第一组，fc/W曲线有明显偏移；第二组，fc/W曲线无偏移或有反向偏移。定义了有氧阈值（Thaer）和乳酸拐点（LTP）。在Thaer和最大工作负荷（Wmax）之间，对fc/W曲线的行为以及[la-]b和[A].[NA]的行为进行了数学描述。计算了静息时、Thaer、LTP、Wmax以及恢复3分钟和6分钟后（Re3/Re6）的fc、收缩压（BPs）、W、[la-]b、[A]和[NA]。两组之间仅在LTP、Re3和Re6时的fc存在显著差异（P<0.05）。在个体fc/W行为与[la-]b、[A]和[NA]的个体时间进程之间未发现显著相关性。然而，[la-]b/W行为与个体儿茶酚胺反应之间存在显著相关性。这些结果以及fc/W曲线顶部不同程度的变平与应激依赖性心肌功能减弱有关这一事实，使我们得出结论：交感神经驱动可能未直接参与负荷依赖性fc与心肌功能之间的调节机制。此外，个体fc/W行为独立于BPs和Wmax，或个体能量供应状况。
