Kanda T, Hara H, Hanaoka T, Kobayashi I
Department of Laboratory Medicine, Gunma University School of Medicine, Maebashi, Japan.
J Med. 1994;25(6):383-7.
A 56-year-old Japanese male patient with Down's syndrome was bitten by a hepatitis B envelope antigen (HBeAg) carrier and become an asymptomatic HBeAg carrier without seroconversion. His mitogen response of T cells was poor compared with that of healthy controls. An impaired T cell response to hepatitis B virus infection may be responsible for the HBeAg carrier with Down's syndrome.
一名患有唐氏综合征的56岁日本男性患者被一名乙肝e抗原(HBeAg)携带者咬伤,成为一名无症状HBeAg携带者且未发生血清学转换。与健康对照相比,他的T细胞丝裂原反应较差。T细胞对乙肝病毒感染的反应受损可能是该唐氏综合征患者成为HBeAg携带者的原因。