Boyd K G, Harper M K, Faulkner D J
Scripps Institution of Oceanography, University of California, San Diego, La Jolla 92093-0212, USA.
J Nat Prod. 1995 Feb;58(2):302-5. doi: 10.1021/np50116a027.
The major metabolite of the Philippine sponge Oceanapia sp. is the antimicrobial alkaloid oceanapamine [1], which was isolated as a trifluoroacetate salt. The structure and the absolute configuration of oceanapamine, which consists of a monocyclic sesquiterpene attached to a histamine residue, were elucidated by interpretation of spectroscopic data.
菲律宾海绵Oceanapia sp.的主要代谢产物是抗菌生物碱海纳帕明[1]，它是以三氟乙酸盐的形式分离得到的。海纳帕明由一个与组胺残基相连的单环倍半萜组成，通过光谱数据解析阐明了其结构和绝对构型。
