Spence K F, Bright R W, Fitzgerald S P, Sell K W
J Bone Joint Surg Am. 1976 Jul;58(5):636-41.
One hundred and forty-four solitary bone cysts were treated by curettage and packing with freeze-dried crushed cortical-bone allograft. One hundred and eight healed primarily. There was a higher rate of recurrence in young patients (less than ten years old), in active cysts, in females, and in incompletely packed cysts. However, of the cysts that were completely packed, 88 per cent healed. These data show that freeze-dried allogeneic crushed cortical bone is superior to similiarly processed cancellous bone and gives results similar to those achieved with fresh autogenous cancellous bone. Orthopaedic surgeons should therefore consider the use of freeze-dried allogeneic crushed cortical bone instead of autogenous grafts to avoid the morbidity and increased risk of complications associated with the procedure to obtain the autogenous bone.
144例孤立性骨囊肿采用刮除术并植入冻干粉碎皮质骨同种异体骨进行治疗。108例一期愈合。年轻患者(小于10岁)、活动期囊肿、女性患者以及填充不完全的囊肿复发率较高。然而,在完全填充的囊肿中,88%实现了愈合。这些数据表明,冻干同种异体粉碎皮质骨优于同样处理的松质骨,其效果与新鲜自体松质骨相似。因此,骨科医生应考虑使用冻干同种异体粉碎皮质骨而非自体移植物,以避免获取自体骨手术相关的发病率和并发症风险增加。