Gueye A, Jongejan F, Mbengue M, Diouf A, Uilenberg G
ISRA, Département de Recherches sur les Productions et la Santé animales, Dakar, Sénégal.
Rev Elev Med Vet Pays Trop. 1994;47(4):401-4.
The results are given of a field trial using a Senegalese stock of Cowdria ruminantium which had been attenuated by passage in cell culture. Thirty vaccinated and thirty control sheep were exposed in the Niayes region of Senegal and were monitored daily. In the control group, 22 animals died of heartwater, associated in one case with anaplasmosis. In the vaccinated group, 13 animals died; Cowdria was found only in two sheep which had previously suffered from ehrlichiosis or anaplasmosis; three other cases of ehrlichiosis and two of anaplasmosis were also observed among these 13 animals. The resistance of the two vaccinated animals which showed Cowdria in their cerebral cortex was apparently lowered by the intercurrent infections. The other animals of the vaccinated group showed no evidence of Cowdria infection.
给出了使用经细胞培养传代减毒的塞内加尔株反刍兽考德里氏体进行的田间试验结果。30只接种疫苗的绵羊和30只对照绵羊在塞内加尔的尼亚耶斯地区暴露，并每天进行监测。在对照组中，22只动物死于心水病，其中1例与无浆体病有关。在接种疫苗的组中，13只动物死亡；仅在2只先前患有埃立克体病或无浆体病的绵羊中发现了考德里氏体；在这13只动物中还观察到另外3例埃立克体病和2例无浆体病。两只在大脑皮层中显示有考德里氏体的接种疫苗动物的抵抗力显然因并发感染而降低。接种疫苗组的其他动物没有考德里氏体感染的迹象。
