Steiner A, Vetter W
Departement für Innere Medizin, Medizinische Poliklinik, Universitätsspital Zürich.
Ther Umsch. 1995 May;52(5):350-4.
The laboratory examinations are more and more significant in the practical internal medicine. The results are basic for decision-making in medicine. The patients are asking for check-up examinations, including screening examinations in the laboratory. We try to compare the significance of two important laboratory tests. The C-reactive protein (CRP) is very sensitive and allows a graduation of the inflammatory reaction. It is useful to take the CRP in a valuable screening examination. Compared with the erythrocyte sedimentation rate (ESR), an elevated CRP always signifies an organic illness. A normal ESR has a poor predictive value. An elevated ESR supports only the history and the clinical findings of a suspected diagnoses. There is no possibility to screen patients without symptoms by ESR. We use ESR to follow-up diseases like arteritis temporalis and polymyalgia rheumatica and to measure the therapeutic effect.
实验室检查在临床内科实践中越来越重要。检查结果是医学决策的基础。患者要求进行检查，包括实验室筛查检查。我们试图比较两项重要实验室检查的意义。C反应蛋白（CRP）非常敏感，能够对炎症反应进行分级。在有价值的筛查检查中检测CRP很有用。与红细胞沉降率（ESR）相比，CRP升高总是意味着存在器质性疾病。ESR正常时预测价值较差。ESR升高仅支持疑似诊断的病史和临床发现。无法通过ESR对无症状患者进行筛查。我们用ESR来随访颞动脉炎和风湿性多肌痛等疾病，并评估治疗效果。
