Meijer C, Bredberg M, Fischer T, Widström L
Strängnäs Armoured Regiment, Sweden.
Contact Dermatitis. 1995 Mar;32(3):147-9. doi: 10.1111/j.1600-0536.1995.tb00804.x.
Piercing the earlobes has increased in popularity among males in recent years. This habit would be expected to increase the incidence of nickel and cobalt sensitization. Patch testing with nickel sulfate and cobalt chloride was performed in 520 young Swedish men doing compulsory military service. The overall frequency of nickel/cobalt positive tests was 4.2%. The prevalence of nickel/cobalt positive tests was significantly higher (p < 0.05) in 152 men with pierced earlobes (7.9%) than in those 368 with unpierced earlobes (2.7%). A history of hand eczema (7/152 = 4.6%) or other types of eczema (22/152 = 14.5%) in individuals with pierced earlobes was no more common than in those with unpierced earlobes: 24/368 = 6.5% and 51/386 = 13.9%, respectively (n.s.). Hand eczema was no more common in sensitized (1/22 = 4.5%) than in nonsensitized individuals (32/498 = 6.4%) (n.s.).
近年来，在男性中穿耳洞越来越流行。这种习惯预计会增加镍和钴致敏的发生率。对520名正在服义务兵役的瑞典年轻男性进行了硫酸镍和氯化钴的斑贴试验。镍/钴阳性试验的总体频率为4.2%。152名有耳洞的男性中镍/钴阳性试验的患病率（7.9%）显著高于368名无耳洞的男性（2.7%）（p<0.05）。有耳洞的个体中手部湿疹病史（7/152 = 4.6%）或其他类型湿疹病史（22/152 = 14.5%）并不比无耳洞的个体更常见：分别为24/368 = 6.5%和51/386 = 13.9%（无统计学差异）。手部湿疹在致敏个体（1/22 = 4.5%）中并不比未致敏个体（32/498 = 6.4%）更常见（无统计学差异）。
