Paweska J T, Gerdes T, Van Heerden J
Onderstepoort Veterinary Institute, Division Virology, Republic of South Africa.
J S Afr Vet Assoc. 1994 Jun;65(2):64-6.
Rabbit hyperimmune serum prepared against a donkey alphaherpesvirus isolate (M7/91), and against EHV-1 and EHV-4 was used to characterise the antigenic relationship between these 3 viruses. Serum from immunised rabbits was always more specific for homologous virus and showed different cross reactivity for heterologous virus. It was concluded that the immunologic relationship between the M7/91 isolate and EHV-1, was closer than that between this isolate and EHV-4. A serological survey of donkeys (n = 116) and horses (n = 57) revealed evidence of the presence of neutralising antibody to M7/91 in their sera. The titres of antibody to M7/91 in donkeys, ranged from 1:32-1 > or = 256 and was significantly higher than antibody titres to EHV-1 and EHV-4, while in horses, titres were lower but comparable to equine herpesvirus 1 and 4.
用针对驴α疱疹病毒分离株（M7/91）、马疱疹病毒1型（EHV-1）和马疱疹病毒4型（EHV-4）制备的兔超免疫血清来表征这三种病毒之间的抗原关系。免疫兔的血清对同源病毒总是更具特异性，对异源病毒表现出不同的交叉反应性。得出的结论是，M7/91分离株与EHV-1之间的免疫关系比该分离株与EHV-4之间的免疫关系更密切。对116头驴和57匹马进行的血清学调查显示，在它们的血清中存在针对M7/91的中和抗体。驴血清中针对M7/91的抗体效价范围为1:32至1≥256，显著高于针对EHV-1和EHV-4的抗体效价，而在马中，抗体效价较低，但与马疱疹病毒1型和4型相当。
