Engels M, Nowotny N, Metzler A E, Wyler R, Bürki F
Microbiologica. 1986 Apr;9(2):221-34.
An EHV 1 isolate from the Lippizan Stud at Piber, which caused the abortion and paresis outbreak in 1983, was investigated using 3 known subtype 1 and 2 subtype 2 strains for comparison. Broad-scale restriction enzyme analysis as well as cross-neutralization with hyperimmune sera produced in rabbits were performed, and SDS-PAGE of infected cell proteins was conducted on a limited scale. The Piber isolate was clearly classified as a subtype 1 strain of EHV 1, and showed closest resemblance in its restriction patterns with a British EHV 1 strain, which originated from an outbreak with paretic symptoms. A second Piber isolate from the same outbreak examined to limited extent only was practically indistinguishable from the first one, as could have been expected. A thoroughly controlled systematic vaccination program with existing commercial vaccines against EHV 1 should protect the endangered Lippizan horses population against the abortigenic and less certainly against the paretic syndromes caused by this virus. According to data presented, a protection against respiratory disease is less probable.
对1983年在皮伯尔的利皮扎马种马场引发流产和轻瘫疫情的一株马疱疹病毒1型（EHV 1）分离株进行了研究，使用3株已知的1型和2株2型毒株作为对照。进行了广泛的限制性内切酶分析以及与兔产生的超免疫血清的交叉中和试验，并对感染细胞蛋白进行了有限规模的SDS - 聚丙烯酰胺凝胶电泳。皮伯尔分离株被明确归类为EHV 1的1型毒株，其限制性图谱与一株源自伴有轻瘫症状疫情的英国EHV 1毒株最为相似。同一疫情中分离出的另一株皮伯尔分离株仅进行了有限程度的检测，正如预期的那样，与第一株几乎无法区分。使用现有的商业EHV 1疫苗进行全面控制的系统疫苗接种计划，应能保护濒危的利皮扎马种群免受该病毒引起的流产综合征影响，对于轻瘫综合征的预防效果则不太确定。根据所提供的数据，预防呼吸道疾病的可能性较小。
