Lambert J R, Lin S K, Aranda-Michel J
Gastroenterology Research Group, Mornington Peninsula Hospital, Frankston, Victoria, Australia.
Scand J Gastroenterol Suppl. 1995;208:33-46. doi: 10.3109/00365529509107760.
Helicobacter pylori is an important cause of chronic active gastritis and is strongly associated with peptic ulcer disease and gastric cancer. H. pylori colonizes the surface of the gastric epithelium with production of a number of factors, resulting in inflammation and an altered mucosa. H. pylori infection occurs world-wide and the mode of transmission most likely is from human to human via the fecal-oral and/or the oral-oral route. Treatment and, in the future, prevention of this infection may result in a marked diminution of upper gastrointestinal tract disease.
幽门螺杆菌是慢性活动性胃炎的重要病因，与消化性溃疡病和胃癌密切相关。幽门螺杆菌通过产生多种因子定植于胃上皮表面，导致炎症和黏膜改变。幽门螺杆菌感染在全球范围内均有发生，其传播途径很可能是人与人之间通过粪-口和/或口-口途径传播。对这种感染的治疗以及未来的预防可能会显著减少上消化道疾病的发生。
