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香港的药物过量及其他中毒情况——威尔士亲王医院(沙田)的经验

Drug overdosage and other poisoning in Hong Kong--the Prince of Wales Hospital (Shatin) experience.

作者信息

Chan T Y, Critchley J A, Chan M T, Yu C M

机构信息

Department of Clinical Pharmacology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N.T.

出版信息

Hum Exp Toxicol. 1994 Jul;13(7):512-5. doi: 10.1177/096032719401300711.

DOI:10.1177/096032719401300711
PMID:7917510
Abstract

From 1988 to 1991, 732 patients (91.1% Chinese) were admitted to four general medical wards at the Prince of Wales Hospital in Hong Kong with acute poisoning. The patients were predominantly female (68.9%) and relatively young (86.3% below the age of 40). Further analysis of 655 patients indicates that the vast majority of patients (96%) were admitted after self-poisoning with drugs or chemicals while 4% of cases were due to accidental poisoning. The main agents used by the former group included hypnotics/sedatives (33.1%), household products (15.7%), and analgesics (13.7%). There were nine deaths (1.4%). When compared to other Western countries, two important variations in the pattern of acute poisoning were seen. A substantial proportion of drugs ingested by our patients were not precisely identified. 'Dettol', a household product, was commonly used for self-poisoning in Hong Kong. Territory-wide studies of longer duration are needed to provide the physicians in Hong Kong with much needed information on the incidence and the pattern of acute poisoning.

摘要

1988年至1991年期间,香港威尔士亲王医院的四个普通内科病房收治了732例急性中毒患者(其中91.1%为中国人)。患者以女性为主(68.9%),且相对年轻(86.3%年龄在40岁以下)。对655例患者的进一步分析表明,绝大多数患者(96%)是在自行服用药物或化学品中毒后入院的,而4%的病例是由于意外中毒。前一组使用的主要药物包括催眠药/镇静剂(33.1%)、家用产品(15.7%)和镇痛药(13.7%)。有9例死亡(1.4%)。与其他西方国家相比,急性中毒模式出现了两个重要差异。我们的患者摄入的很大一部分药物无法准确识别。家用产品“滴露”在香港常用于自我中毒。需要进行更长期的全港性研究,以便为香港的医生提供有关急性中毒发病率和模式的急需信息。

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