Middleton H C, Ashby M
Department of Psychiatry, Nottingham University, United Kingdom.
Acta Psychiatr Scand. 1995 Feb;91(2):108-13. doi: 10.1111/j.1600-0447.1995.tb09749.x.
Cardiovascular measures (spectral derivatives of heart rate variability, the blood pressure response to standing and plasma noradrenaline levels) have been shown to change as clinical recovery follows the treatment of panic disorder patients with either imipramine or cognitive therapy. These findings can be interpreted as evidence of changes in baroreflex modulation, an important feature of the cardiovascular expression of arousal. This offers further evidence of a dysregulation of arousal in this disorder.
心血管指标（心率变异性的频谱导数、站立时的血压反应和血浆去甲肾上腺素水平）已显示出会随着惊恐障碍患者接受丙咪嗪或认知疗法治疗后临床症状的缓解而发生变化。这些发现可被解释为压力反射调节发生变化的证据，压力反射调节是觉醒的心血管表现的一个重要特征。这进一步证明了该疾病中觉醒调节失调。
