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补充硒对大鼠多不饱和脂肪酸的影响。

Effect of selenium supplementation on polyunsaturated fatty acids in rats.

作者信息

Crespo A M, Reis M A, Lança M J

机构信息

Departamento de Zoologia e Antropologia, Faculdade de Ciências de Lisboa, Portugal.

出版信息

Biol Trace Elem Res. 1995 Jan-Mar;47(1-3):335-41. doi: 10.1007/BF02790135.

DOI:10.1007/BF02790135
PMID:7779567
Abstract

The purpose of this work was to study plasma, adipose tissue, and liver fatty acids percentages of Wistar rats that drank water supplemented with several levels of sodium selenite for 1, 3, and 6 mo. In a general way, percentages of saturated, monounsaturated, and polyunsaturated fatty acids of supplemented groups were not different from those obtained with nontreated animals in the analyzed tissues. However, in rats supplemented with 0.5 ppm Se, mainly in adipose tissue, a polyunsaturated fatty acids increase (p < 0.005) was observed for all times of treatment. This could suggest that 0.5 ppm Se supplement probably exercises a protective role on polyunsaturated fatty acids in that tissue. Supplements of 6.0, 15.0, and 54.0 ppm Se did not change unsaturation levels of fatty acids in the analyzed tissues.

摘要

本研究旨在探讨饮用添加不同水平亚硒酸钠的水1个月、3个月和6个月的Wistar大鼠血浆、脂肪组织和肝脏中的脂肪酸百分比。总体而言,在分析的组织中,补充组的饱和脂肪酸、单不饱和脂肪酸和多不饱和脂肪酸百分比与未处理动物的百分比没有差异。然而,在补充0.5 ppm硒的大鼠中,主要是在脂肪组织中,在所有治疗时间均观察到多不饱和脂肪酸增加(p < 0.005)。这可能表明,补充0.5 ppm硒可能对该组织中的多不饱和脂肪酸起到保护作用。补充6.0、15.0和54.0 ppm硒并未改变分析组织中脂肪酸的不饱和水平。

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Plasma and liver selenium levels in the rat during supplementation with 0.5, 2, 6, and 15 ppm selenium in drinking water.在给大鼠饮用含0.5、2、6和15 ppm硒的水进行补充期间,大鼠血浆和肝脏中的硒水平。
Biol Trace Elem Res. 1993 Aug;38(2):139-47. doi: 10.1007/BF02784050.
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