Arria A M, Dohey M A, Mezzich A C, Bukstein O G, Van Thiel D H
University of Pittsburgh School of Medicine, Department of Psychiatry, Pennsylvania, USA.
J Adolesc Health. 1995 Mar;16(3):226-31. doi: 10.1016/1054-139X(94)00066-N.
Few studies have examined the impact of alcohol abuse on the health status of adolescents. The purpose of this investigation was to determine whether adolescents with a diagnosis of alcohol abuse differed from controls on the frequency of self-reported health problems, clinical signs and symptoms detected upon clinical examination, and liver injury test results.
Cases were ascertained from in-patient drug and alcohol treatment centers. Age- and sex-matched controls were recruited from community sources. The Health Problems Checklist (HPC) was used to measure self-reported problems; the clinical examination was performed by a physician or a physician's assistant.
Alcohol-abusing adolescents reported significantly more physical symptoms than did controls as measured by the HPC. The results of the clinical examination revealed a low prevalence of overt abnormalities in both groups, however, alcohol-abusing adolescents reported a higher frequency of appetite changes, weight loss, eczema, headaches and episodes of loss of consciousness than did controls. As expected, alcohol-abusing adolescents had significantly higher levels of ALT, AST and GGTP as compared to controls.
The findings of this study are generalizable only to in-patient adolescent alcohol abusers. In this study, alcohol abuse was also associated frequently with psychiatric disorders, drug abuse, cigarette smoking, and low parental education. Future studies using larger sample sizes should address the importance of social environmental and behavioral variables in moderating the relationship between alcohol abuse and decreased health status in adolescents.
很少有研究探讨酒精滥用对青少年健康状况的影响。本调查的目的是确定诊断为酒精滥用的青少年在自我报告的健康问题频率、临床检查中发现的临床体征和症状以及肝损伤检测结果方面是否与对照组存在差异。
病例来自住院药物和酒精治疗中心。年龄和性别匹配的对照组从社区来源招募。使用健康问题清单(HPC)来衡量自我报告的问题;临床检查由医生或医师助理进行。
通过HPC测量,酗酒青少年报告的身体症状明显多于对照组。临床检查结果显示两组明显异常的患病率较低,然而,酗酒青少年报告食欲改变、体重减轻、湿疹、头痛和意识丧失发作的频率高于对照组。正如预期的那样,酗酒青少年的ALT、AST和GGTP水平明显高于对照组。
本研究的结果仅适用于住院青少年酗酒者。在本研究中,酒精滥用还经常与精神障碍、药物滥用、吸烟和低父母教育程度相关。未来使用更大样本量的研究应探讨社会环境和行为变量在调节酒精滥用与青少年健康状况下降之间关系中的重要性。