Zaridze D G, Zemlianaia G M, Aĭtakov Z N
Vestn Ross Akad Med Nauk. 1995(4):6-10.
The results of a case-control study of lung cancer risk in female non-smokers in Moscow are presented in the paper. The increase in a risk of lung cancer was found to be associated with outdoor pollution, the closure of the residence to chemical industry and ferrous and non-ferrous smelters, environmental tobacco smoke from husbands and exposure to radon (Rn) at home. The relative risk of lung cancer (RR) for those living in high air polluted versus relatively pure areas was 2.6 (95% CI = 1.2-5.6). RR of lung cancer related to the closure of the residence to chemical industry and ferrous and non-ferrous smelters were 2.0 (95% CI = 1.0-3.9) and 1.75 (95% CI = 1.0-3.1). The analysis has shown that there is an increase in lung cancer risk in women whose husbands smoke, which is as high as 1.9 (95% CI = 1.3-2.9). Lung cancer risk is associated with levels of exposure to Rn in the dwellings: RR was 2.48 (95% CI = 1.4-4.3) for the Rn concentration of > 24.3 Bq/m3 versus < 13 Bq/m3.
本文展示了一项针对莫斯科女性非吸烟者肺癌风险的病例对照研究结果。研究发现，肺癌风险的增加与室外污染、住所靠近化工、黑色及有色金属冶炼厂、丈夫的环境烟草烟雾以及家中氡（Rn）暴露有关。生活在空气污染严重地区与相对纯净地区的人群相比，肺癌相对风险（RR）为2.6（95%置信区间=1.2 - 5.6）。与住所靠近化工、黑色及有色金属冶炼厂相关的肺癌RR分别为2.0（95%置信区间=1.0 - 3.9）和1.75（95%置信区间=1.0 - 3.1）。分析表明，丈夫吸烟的女性患肺癌风险增加，高达1.9（95%置信区间=1.3 - 2.9）。肺癌风险与住所中的Rn暴露水平有关：Rn浓度>24.3 Bq/m³与<13 Bq/m³相比，RR为2.48（95%置信区间=1.4 - 4.3）。
