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[肾综合征出血热尸检睾丸组织的光镜和免疫组化研究]

[A light-microscopic and immunohistochemical study in testis tissue from hemorrhagic fever with renal syndrome autopsies].

作者信息

Wang Z, Xing S, Li P

机构信息

Department of Pathology, First Affiliated Hospital, Hubei Medical University, Wuhan.

出版信息

Zhonghua Yi Xue Za Zhi. 1995 Mar;75(3):147-8, 189-90.

PMID:7780819
Abstract

Testis tissues from 13 cases of hemorrhagic fever with renal syndrome (HFRS) were studied by light-microscopy and immunogold-silver staining (IGSS). Under routine light microscopy, the pathological lesions were found frequently in the spermatogenic epithelia, the basement membrane in the seminiferous tubules, and the mesenchyme around the tubules. Immunohistochemical studies showed that there were immune complexes (IgG) deposited mainly in the basement membrane in the tubules and interstitial cells, endothelial cells, and red cells of the small vessels around tubules mesenchyme. The injury mechanism is that the immuno complexes (IgG) are deposited in testis tissues from HFRS autopsies.

摘要

对13例肾综合征出血热(HFRS)患者的睾丸组织进行了光学显微镜和免疫金银染色(IGSS)研究。在常规光学显微镜下,生精上皮、曲细精管基底膜以及曲细精管周围的间质中常发现病理损伤。免疫组织化学研究表明,免疫复合物(IgG)主要沉积在曲细精管基底膜以及间质细胞、内皮细胞和曲细精管周围间质中小血管的红细胞中。损伤机制是免疫复合物(IgG)沉积于HFRS尸检的睾丸组织中。

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