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灌注型视网膜中央静脉阻塞的自然病程。

Natural course of perfused central retinal vein occlusion.

作者信息

Chen J C, Klein M L, Watzke R C, Handelman I L, Robertson J E

机构信息

Department of Ophthalmology, McGill University, Montreal, Que.

出版信息

Can J Ophthalmol. 1995 Feb;30(1):21-4.

PMID:7780892
Abstract

OBJECTIVE

To investigate the visual prognosis in perfused (nonischemic) central retinal vein occlusion (CRVO), to determine the frequency of conversion from perfused to nonperfused CRVO, and to identify risk factors for poor visual outcome.

DESIGN

Case series.

SETTING

Retina referral centre in Portland, Ore.

PATIENTS

Fifty-eight patients (59 eyes) with perfused CRVO followed for at least 1 year (average 2.5 years).

MAIN OUTCOME MEASURES

Visual acuity, progression to nonperfused CRVO.

RESULTS

At the final follow-up visit the visual acuity had improved by two or more lines in 9 eyes (15%), remained the same in 33 eyes (56%) and decreased by two or more lines in 17 eyes (29%). Factors significantly related to visual outcome were initial visual acuity (p = 0.0001) and age, older patients having a worse visual outcome (p = 0.0029). Nine eyes (15%) progressed to nonperfused CRVO. None of the factors analysed, including age, sex, duration of symptoms and initial visual acuity, were predictive of progression.

CONCLUSIONS

Perfused CRVO frequently results in significant, permanent visual loss, and a poor visual outcome is most likely in older patients and those with poor initial visual acuity.

摘要

目的

研究灌注型(非缺血性)视网膜中央静脉阻塞(CRVO)的视力预后,确定灌注型CRVO转变为非灌注型CRVO的频率,并识别视力预后不良的危险因素。

设计

病例系列研究。

地点

俄勒冈州波特兰的视网膜转诊中心。

患者

58例(59只眼)灌注型CRVO患者,随访至少1年(平均2.5年)。

主要观察指标

视力,进展为非灌注型CRVO。

结果

在最后一次随访时,9只眼(15%)的视力提高了两行或更多行,33只眼(56%)视力保持不变,17只眼(29%)视力下降了两行或更多行。与视力预后显著相关的因素是初始视力(p = 0.0001)和年龄,年龄较大的患者视力预后较差(p = 0.0029)。9只眼(15%)进展为非灌注型CRVO。所分析的因素,包括年龄、性别、症状持续时间和初始视力,均不能预测病情进展。

结论

灌注型CRVO常导致显著的永久性视力丧失,年龄较大和初始视力较差的患者视力预后最差。

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